Literature summary for 3.4.21.22 extracted from

Rohlena, J.; Kolkman, J.A.; Boertjes, R.C.; Mertens, K.; Lenting, P.J.
Residues Phe342-Asn346 of activated coagulation factor IX contribute to the interaction with low density lipoprotein receptor-related protein (2003), J. Biol. Chem., 278, 9394-9401.

Search for more literature for 3.4.21.22

Activating Compound

Activating Compound	Comment	Organism	Structure
Factor VIIIa	-	Homo sapiens
phospholipid membrane	-	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
-	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
K265A	no change in binding of anti fIX monoclonal antibodies CLB-fIX 14 and CLB-fIX 13	Homo sapiens
N346D	no change in binding of anti fIX monoclonal antibodies CLB-fIX 14, no binding of anti fIX monoclonal antibody CLB-fIX 13	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
antithrombin	-	Homo sapiens

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Ca2+	-	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
factor X + H2O	Homo sapiens	-	factor Xa	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant fIXa	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CH3SO2-D-Leu-Gly-L-Arg-p-nitroanilide + H2O	-	Homo sapiens	CH3SO2-D-Leu-Gly-L-Arg + p-nitroaniline	-	?
factor X + H2O	-	Homo sapiens	factor Xa	-	?

Synonyms

Synonyms	Comment	Organism
FIXa	-	Homo sapiens

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Release 2023.1 (January 2023)