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Literature summary for 3.4.21.22 extracted from

  • Blostein, M.D.; Furie, B.C.; Rajotte, I.; Furie, B.
    The Gla domain of factor IXa binds to factor VIIIa in the tenase complex (2003), J. Biol. Chem., 278, 31297-31302.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
phospholipid membrane very strong activation of factor IXa Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
FIX1-47 peptide benzoylphenylalanine containing peptide, 0.038 mM, 50% inhibition Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
factor X + H2O Homo sapiens
-
factor Xa
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
factor X + H2O
-
Homo sapiens factor Xa
-
?

Cofactor

Cofactor Comment Organism Structure
Factor VIIIa factor IXa binds to factor VIIIa on phospholipid membranes to form an enzymatic complex, the tenase complex Homo sapiens