Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Factor VIIIa | - |
Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
antithrombin | almost no inhibition in the absence of heparin, strong acceleration of the inhibition rate in the presence of heparin and physiologic levels of Ca2+ | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | 4-8fold allosteric activation at 5 mM | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
factor X + H2O | Homo sapiens | - |
factor Xa | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-cyclohexylglycyl-Gly-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | D-cyclohexylglycyl-Gly-Arg + 7-amino-4-methylcoumarin | - |
? | |
D-cyclohexylglycyl-Gly-Arg-p-nitroanilide + H2O | - |
Homo sapiens | D-cyclohexylglycyl-Gly-Arg + p-nitroaniline | - |
? | |
factor X + H2O | - |
Homo sapiens | factor Xa | - |
? |