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Literature summary for 3.4.21.21 extracted from
- Molecular determinants involved in differential behaviour between soluble tissue factor and full-length tissue factor towards factor VIIa (2017), Phys. Chem. Chem. Phys., 19, 22230-22242 .
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| tissue factor | binding of tissue factor with factor FVIIa only partially enhances the enzyme's proteolytic activity. Soluble tissue factor has a lower binding capacity with the enzyme compared to membrane bound full-length tissue factor | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Homo sapiens | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| factor IX + H2O | Homo sapiens | - |
factor IXa + ? | - |
? |  |
| Factor X + H2O | Homo sapiens | - |
Factor Xa + ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| factor IX + H2O | - |
Homo sapiens | factor IXa + ? | - |
? | |
| Factor X + H2O | - |
Homo sapiens | Factor Xa + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| FVIIa | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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