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Literature summary for 3.4.21.21 extracted from

  • Vadivel, K.; Agah, S.; Messer, A.S.; Cascio, D.; Bajaj, M.S.; Krishnaswamy, S.; Esmon, C.T.; Padmanabhan, K.; Bajaj, S.P.
    Structural and functional studies of gamma-carboxyglutamic acid domains of factor VIIa and activated protein C: role of magnesium at physiological calcium (2013), J. Mol. Biol., 425, 1961-1981.
    View publication on PubMedView publication on EuropePMC
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Activating Compound

Activating Compound Comment Organism Structure
tissue factor
-
 Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ Mg2+ potentiates the activation of factor X and factor IX by factor VIIa Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
factor IX + H2O Homo sapiens
-
 factor IXa + ?
-
 ?
Factor X + H2O Homo sapiens
-
 Factor Xa + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P08709
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
factor IX + H2O
-
 Homo sapiens factor IXa + ?
-
 ?
Factor X + H2O
-
 Homo sapiens Factor Xa + ?
-
 ?

Synonyms

Synonyms Comment Organism
factor VIIa
-
 Homo sapiens
FVIIa
-
 Homo sapiens