Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.20 extracted from

  • Groborz, K.; Kolt, S.; Kasperkiewicz, P.; Drag, M.
    Internally quenched fluorogenic substrates with unnatural amino acids for cathepsin G investigation (2019), Biochimie, 166, 103-111 .
    View publication on PubMed
Search for more literature for 3.4.21.20

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(7-aminocoumarin-4-yl)acetyl-Gly-His(Bzl)-Tle-Pro-Phe-norvaline-Asp-3-Pal-Gly-Lys(DNP)-Gly-NH2 + H2O
-
 Homo sapiens (7-aminocoumarin-4-yl)acetyl-Gly-His(Bzl)-Tle-Pro-Phe + norvaline-Asp-3-Pal-Gly-Lys(DNP)-Gly-NH2
-
 ?
(7-aminocoumarin-4-yl)acetyl-Gly-His(Bzl)-Tle-Pro-Phe-Ser-Asp-Lys(Tfa)-Gly-Lys(DNP)-Gly-NH2 + H2O
-
 Homo sapiens (7-aminocoumarin-4-yl)acetyl-Gly-His(Bzl)-Tle-Pro-Phe + Ser-Asp-Lys(Tfa)-Gly-Lys(DNP)-Gly-NH2
-
 ?
(7-aminocoumarin-4-yl)acetyl-Gly-His(Bzl)-Tle-Pro-Phe-Ser-Asp-Met(O)-Gly-Lys(DNP)-Gly-NH2 + H2O
-
 Homo sapiens (7-aminocoumarin-4-yl)acetyl-Gly-His(Bzl)-Tle-Pro-Phe + Ser-Asp-Met(O)-Gly-Lys(DNP)-Gly-NH2
-
 ?
(7-aminocoumarin-4-yl)acetyl-Gly-Phe(F)5-Tle-Pro-Phe-norvaline-Asp-3-Pal-Gly-Lys(DNP)-Gly-NH2 + H2O
-
 Homo sapiens (7-aminocoumarin-4-yl)acetyl-Gly-Phe(F)5-Tle-Pro-Phe + norvaline-Asp-3-Pal-Gly-Lys(DNP)-Gly-NH2
-
 ?
(7-aminocoumarin-4-yl)acetyl-Gly-Phe(F)5-Tle-Pro-Phe-norvaline-Asp-Met(O)2-Gly-Lys(DNP)-Gly-NH2 + H2O
-
 Homo sapiens (7-aminocoumarin-4-yl)acetyl-Gly-Phe(F)5-Tle-Pro-Phe + norvaline-Asp-Met(O)2-Gly-Lys(DNP)-Gly-NH2
-
 ?

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
0.154
-
 (7-aminocoumarin-4-yl)acetyl-Gly-Phe(F)5-Tle-Pro-Phe-norvaline-Asp-3-Pal-Gly-Lys(DNP)-Gly-NH2 at pH 7.4 and 37°C Homo sapiens
0.17
-
 (7-aminocoumarin-4-yl)acetyl-Gly-Phe(F)5-Tle-Pro-Phe-norvaline-Asp-Met(O)2-Gly-Lys(DNP)-Gly-NH2 at pH 7.4 and 37°C Homo sapiens
0.179
-
 (7-aminocoumarin-4-yl)acetyl-Gly-His(Bzl)-Tle-Pro-Phe-Ser-Asp-Lys(Tfa)-Gly-Lys(DNP)-Gly-NH2 at pH 7.4 and 37°C Homo sapiens
0.191
-
 (7-aminocoumarin-4-yl)acetyl-Gly-His(Bzl)-Tle-Pro-Phe-norvaline-Asp-3-Pal-Gly-Lys(DNP)-Gly-NH2 at pH 7.4 and 37°C Homo sapiens
0.207
-
 (7-aminocoumarin-4-yl)acetyl-Gly-His(Bzl)-Tle-Pro-Phe-Ser-Asp-Met(O)-Gly-Lys(DNP)-Gly-NH2 at pH 7.4 and 37°C Homo sapiens