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Literature summary for 3.4.21.20 extracted from
- Elastase and cathepsin G from primed leukocytes cleave vascular endothelial cadherin in hemodialysis patients (2014), BioMed Res. Int., 2014, 459640.
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 30000 | - |
x * 30000, SDS-PAGE | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cadherin + H2O | Homo sapiens | - |
? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P08311 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leukocyte | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cadherin + H2O | - |
Homo sapiens | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 30000, SDS-PAGE | Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | level of cathepsin G is reduced in peripheral polymorphonuclear leukocytes of hemodialysis patients, while the mRNA enzyme level is not different | down |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | cathepsin G originating from primed peripheral polymorphonuclear leukocytes of hemodialysis patients can initiate endothelial dysfunction | Homo sapiens |
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Release 2023.1 (January 2023)
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