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Literature summary for 3.4.21.20 extracted from

  • Reich, M.; Lesner, A.; Legowska, A.; Sienczyk, M.; Oleksyszyn, J.; Boehm, B.O.; Burster, T.
    Application of specific cell permeable cathepsin G inhibitors resulted in reduced antigen processing in primary dendritic cells (2009), Mol. Immunol., 46, 2994-2999.
    View publication on PubMed
Search for more literature for 3.4.21.20

Inhibitors

Inhibitors Comment Organism Structure
CatG-specific inhibitor I reversible inhibitor Homo sapiens
[Nphe,Npip,Nleu]SFTI-1 0.1 mM Homo sapiens
[Phe(4-guanidine)]SFTI-1 0.1 mM Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
intracellular
-
 Homo sapiens 5622
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
peripheral blood mononuclear cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hemagglutinin + H2O assay at pH 5.0, 37°C Homo sapiens ?
-
 ?
tetanus toxin C-fragment + H2O assay at pH 5.0, 37°C Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
CatG
-
 Homo sapiens
cathepsin G
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
 assay at Homo sapiens

General Information

General Information Comment Organism
malfunction inhibition of CatG reduces the presentation of antigens to CD4+ T cells Homo sapiens