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Literature summary for 3.4.21.20 extracted from

  • Sedor, J.; Hogue, L.; Akers, K.; Boslaugh, S.; Schreiber, J.; Ferkol, T.
    Cathepsin-G interferes with clearance of Pseudomonas aeruginosa from mouse lungs (2006), Pediatr. Res., 61, 26-31.
    View publication on PubMed
Search for more literature for 3.4.21.20

Protein Variants

Protein Variants Comment Organism
additional information no increased cytokine production and increased bacterial reduction by phagocytosis in infected lungs of enzyme-deficient mice compared to wild-type mice, overview Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus the neutrophil-derived serine protease cathepsin G inhibits the murine host’s ability to clear Pseudomonas aeruginosa, an infection in cystic fibrosis airways causing intense inflammation, from the lung, murine model of endobronchial inflammation, overview ?
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Organism

Organism UniProt Comment Textmining
Mus musculus
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 wild-type strain 129/SvJ
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Source Tissue

Source Tissue Comment Organism Textmining
lung
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 Mus musculus
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neutrophil
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 Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the neutrophil-derived serine protease cathepsin G inhibits the murine host’s ability to clear Pseudomonas aeruginosa, an infection in cystic fibrosis airways causing intense inflammation, from the lung, murine model of endobronchial inflammation, overview Mus musculus ?
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 ?