Literature summary for 3.4.21.119 extracted from

Ishige, S.; Kasamatsu, A.; Ogoshi, K.; Saito, Y.; Usukura, K.; Yokoe, H.; Kouzu, Y.; Koike, H.; Sakamoto, Y.; Ogawara, K.; Shiiba, M.; Tanzawa, H.; Uzawa, K.
Decreased expression of kallikrein-related peptidase 13: possible contribution to metastasis of human oral cancer (2014), Mol. Carcinog., 53, 557-565.

No PubMed abstract available

Search for more literature for 3.4.21.119

Application

Application	Comment	Organism
diagnostics	loss of the enzyme is a potential biomarker for early detection of lymph node metastasis in oral squamous cell carcinoma cell lines	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
the enzyme is encoded on chromosome 19q13.4	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9UKR3	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HSC-3 cell	-	Homo sapiens	-
keratinocyte	oral	Homo sapiens	-
oral squamous cell carcinoma cell	kallikrein-related peptidase 13 is downregulated in oral squamous cell carcinoma cell lines, primary tumors and established cell lines	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
kallikrein-related peptidase 13	-	Homo sapiens
KLK13	-	Homo sapiens

Expression

Organism	Comment	Expression
Homo sapiens	kallikrein-related peptidase 13 is downregulated in oral squamous cell carcinoma cell lines	down

General Information

General Information	Comment	Organism
evolution	the enzyme belongs to the human kallikrein-related peptidase family, which is comprised of 15 serine protease genes on chromosome 19q13.4	Homo sapiens
physiological function	the enzyme may play an important role in regulating cellular migration and invasiveness	Homo sapiens

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Release 2023.1 (January 2023)