Application | Comment | Organism |
---|---|---|
medicine | gene may be involved in the pathogenesis and/or progression of breast cancer and may find applicability as cancer biomarker | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
gene KLK-L4, DNA sequence determination and analysis, gene mapps to chromosome 19q13.3-q13.4, tissue expression analysis | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
polypeptide + H2O | Homo sapiens | - |
peptides | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9UKR3 | GenBank: AF135024; kallikrein-like gene 4, i.e. KLK-L4 | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
Hydrolyses mouse Ren2 protein (a species of prorenin present in the submandibular gland) on the carboxy side of the arginine residue at the Lys-Arg-/- pair in the N-terminus, to yield mature renin | enzyme is a serine protease | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast | - |
Homo sapiens | - |
breast carcinoma cell | down-regulated by steroid hormones | Homo sapiens | - |
additional information | gene is expressed in various tissues | Homo sapiens | - |
prostate | - |
Homo sapiens | - |
salivary gland | - |
Homo sapiens | - |
testis | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
polypeptide + H2O | - |
Homo sapiens | peptides | - |
? |