Application | Comment | Organism |
---|---|---|
analysis | binding assessment of ligands to kallikrein-8 using a residue-wise decomposition of the binding energy. Use of chemical energy-wise decomposition or CHEWD for residue-wise decomposition of binding energies | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-(2-bromobenzene-1-sulfonyl)-5-methyl-3-(2-methyl-4,5-dihydro-1H-imidazol-4-yl)-1H-indole | compound is a promising lead for development of novel kallikrein-8 inhibitors. It binds stably to the kallikrein-8 S1 binding site | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O60259 | - |
- |