Cloned (Comment) | Organism |
---|---|
overexpression of proneuropsin in Spodoptera frugiperda insect cells via baculovirus infection | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
murinoglobulin I | 24% inhibition at enzyme-inhibitor ratio of 1:2; formation of a SDS-stable complex; i.e. MUG I | Mus musculus | |
serine protease inhibitor-3 | formation of a SDS-stable complex, bimolecular kinetics; from pyramidal neurons; slowly and tightly binding inhibitor | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
polypeptide + H2O | Mus musculus | involvement in neural plasticity | peptides | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q61955 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | enzyme contains N-glycosylation sites | Mus musculus |
Purification (Comment) | Organism |
---|---|
recombinant from SF21 insect cells | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | expressed in the forebrain limbic area of adult brain | Mus musculus | - |
neuron | in the hippocampal CA1-CA3 subfields | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
polypeptide + H2O | - |
Mus musculus | peptides | - |
? | |
polypeptide + H2O | involvement in neural plasticity | Mus musculus | peptides | - |
? | |
tert-butyloxycarbonyl-Val-Pro-Arg-4-methylcoumaryl-7-amide + H2O | - |
Mus musculus | tert-butyloxycarbonyl-Val-Pro-Arg + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NP | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Mus musculus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0008 | - |
serine protease inhibitor-3 | complex formation, pH 7.4, 37°C | Mus musculus |