Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Bacillus subtilis | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | - |
- |
- |
Bacillus subtilis PY79 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pro-sigmaK + H2O | - |
Bacillus subtilis | sigmaK + ? | - |
? | |
pro-sigmaK + H2O | - |
Bacillus subtilis PY79 | sigmaK + ? | - |
? |
General Information | Comment | Organism |
---|---|---|
physiological function | a stable association between the membrane-embedded protease SpoIVFB and its substrate requires SpoIVB signaling. The cytoplasmic cystathionine-beta-synthase domain of the SpoIVFB protease is not critical for this interaction or for pro-sigmaK processing. A model explains IVB-dependent cleavage of SpoIVFA on one side of the membrane triggers a conformational change in the membrane-embedded protease from a closed to an open state allowing pro-sigmaK access to the caged interior of the protease | Bacillus subtilis |