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Literature summary for 3.4.21.112 extracted from
- Long-term treatment with moisturizers affects the mRNA levels of genes involved in keratinocyte differentiation and desquamation (2009), Arch. Dermatol. Res., 301, 175-181.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride | - |
Rattus norvegicus |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 35000 | - |
SDS-PAGE, predominant form in non-mineralizing cultures are smaller than 35 kDa | Rattus norvegicus |
| 98000 | - |
SDS-PAGE, expressed as a soluble enzyme in mineralizing UMR 106 cells | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| UMR-106 cell | osteosarcoma cell line used. Mineralizing UMR 106 cells express a 98 kDa active, soluble form of SKI-1 within biomineralization foci. Non-mineralizing UMR cells differentially process SKI-1 into smaller immunoreactive fragments | Rattus norvegicus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SKI-1 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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