Application | Comment | Organism |
---|---|---|
degradation | S1P reduces the size of the luminal domain to prepare ATF6 to be an optimal S2P substrate | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-(2-aminoethyl)-benzenesulfonyl fluoride | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | relocalization of SP1 and SP2 with brefeldin A, reconstitution of the sequential cleavage of ATF6 | Homo sapiens | 5783 | - |
Golgi apparatus | SP1 localizes to the same compartment as SP2, the cis/medial Golgi | Homo sapiens | 5794 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATF6 + H2O | i.e. activating transcription factor 6 | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
S1P | - |
Homo sapiens |