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Literature summary for 3.4.21.112 extracted from
- Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization (1999), Proc. Natl. Acad. Sci. USA, 96, 1321-1326.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi apparatus | - |
Homo sapiens | 5794 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | dependent | Homo sapiens |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 148000 | - |
zymogen, SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | Q9WTZ3 | - |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | - |
Homo sapiens |
| proteolytic modification | proSKI-1 is processed into two membrane-bound forms of SKI-1: 120000 Da and 106000 Da | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adrenal gland | - |
Rattus norvegicus | - |
| bone | - |
Rattus norvegicus | - |
| brain | - |
Rattus norvegicus | - |
| cerebellum | - |
Rattus norvegicus | - |
| intestine | - |
Rattus norvegicus | - |
| kidney | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
| molaris | - |
Rattus norvegicus | - |
| muscle | - |
Rattus norvegicus | - |
| pituitary gland | - |
Rattus norvegicus | - |
| retina | - |
Rattus norvegicus | - |
| skin | - |
Rattus norvegicus | - |
| submaxillary gland | - |
Rattus norvegicus | - |
| thymus | - |
Rattus norvegicus | - |
| thyroid gland | - |
Rattus norvegicus | - |
| tooth | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| brain-derived neurotrophic factor precursor + H2O | cleaves at an RGLTLS site between Thr and Ser | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| S08.063 | Merops ID | Rattus norvegicus |
| S1P | - |
Homo sapiens |
| S1P | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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