Literature summary for 3.4.21.110 extracted from

Brown, C.K.; Gu, Z.Y.; Matsuka, Y.V.; Purushothaman, S.S.; Winter, L.A.; Cleary, P.P.; Olmsted, S.B.; Ohlendorf, D.H.; Earhart, C.A.
Structure of the streptococcal cell wall C5a peptidase (2005), Proc. Natl. Acad. Sci. USA, 102, 18391-18396.

Search for more literature for 3.4.21.110

Application

Application	Comment	Organism
additional information	streptococcal C5a peptidase binding to integrins by the Arg-Gly-Asp motifs may stabilize conformational changes required for substrate binding	Streptococcus agalactiae

Cloned(Commentary)

Cloned (Comment)	Organism
in Escherichia coli B834(DE3)	Streptococcus agalactiae

Crystallization (Commentary)

Crystallization (Comment)	Organism
SCP mutant, by hanging drop method, to 2 A resolution, SCPB composed of five distinct domains, N-terminal subtilisin-like protease domain with a 134-residue protease-associated domain inserted into a loop between two beta-strands, and with one of two Arg-Gly-Asp sequences found in SCPB, at the C-terminus are three fibronectin type III domains, second Arg-Gly-Asp sequence is located between fibronectin type III (1) and fibronectin type III (2)	Streptococcus agalactiae

Crystallization (Comment)

Organism

SCP mutant, by hanging drop method, to 2 A resolution, SCPB composed of five distinct domains, N-terminal subtilisin-like protease domain with a 134-residue protease-associated domain inserted into a loop between two beta-strands, and with one of two Arg-Gly-Asp sequences found in SCPB, at the C-terminus are three fibronectin type III domains, second Arg-Gly-Asp sequence is located between fibronectin type III (1) and fibronectin type III (2)

Streptococcus agalactiae

Protein Variants

Protein Variants	Comment	Organism
D130A/S512A	SCP mutant with 949-residue fragment	Streptococcus agalactiae

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Streptococcus agalactiae	-	group B streptococcus, serotype II strain	-

Purification (Commentary)

Purification (Comment)	Organism
by ion-exchange chromatography	Streptococcus agalactiae

Storage Stability

Storage Stability	Organism
-20°C	Streptococcus agalactiae

Synonyms

Synonyms	Comment	Organism
ScpB	-	Streptococcus agalactiae

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Release 2023.1 (January 2023)