Protein Variants | Comment | Organism |
---|---|---|
D130A | mutant with reduced proteolytic activity | Streptococcus pyogenes |
H193A | mutant with reduced proteolytic activity | Streptococcus pyogenes |
L512A | mutant with reduced proteolytic activity | Streptococcus pyogenes |
N295A | mutant with reduced proteolytic activity | Streptococcus pyogenes |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | inhibition at 10 mM | Streptococcus pyogenes | |
Mn2+ | inhibition at 10 mM | Streptococcus pyogenes | |
additional information | no inhibitor: EDTA | Streptococcus pyogenes | |
NaCl | - |
Streptococcus pyogenes | |
Zn2+ | significant inhibition at 0.1-10 mM | Streptococcus pyogenes |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
chemotaxin C5a | Streptococcus pyogenes | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pyogenes | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Streptococcus pyogenes |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
chemotaxin C5a | - |
Streptococcus pyogenes | ? | - |
? | |
chemotaxin C5a + H2O | - |
Streptococcus pyogenes | ? | - |
? | |
glutathione S-transferase-chemotaxin C5a-GFP + H2O | fusion protein | Streptococcus pyogenes | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
S08.020 | Merops ID | Streptococcus pyogenes |
SCPA | - |
Streptococcus pyogenes |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
65 | - |
85% activity after 30 min, 75% activity after 60 min | Streptococcus pyogenes |
100 | - |
30% activity after boiling for 10 min | Streptococcus pyogenes |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
- |
Streptococcus pyogenes |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7 | - |
activity sharply declines below pH 7 | Streptococcus pyogenes |