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Literature summary for 3.4.21.110 extracted from

  • Cleary, P.P.; Prahbu, U.; Dale, J.B.; Wexler, D.E.; Handley, J.
    Streptococcal C5a peptidase is a highly specific endopeptidase (1992), Infect. Immun., 60, 5219-5223.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.110

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
chemotaxin C5a + H2O Streptococcus pyogenes
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Streptococcus pyogenes
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chemotaxin C5a cleavage site is His-Lys rather than Lys-Asp, native protein is resistant to cleavage, suggesting that His-Lys bond is inaccessible prior to proteolytic cleavage by C5 convertase Streptococcus pyogenes ?
-
 ?
chemotaxin C5a + H2O
-
 Streptococcus pyogenes ?
-
 ?
Cys-Val-Val-Ala-Ser-Gln-Leu-Arg-Ala-Asn-Ile-His-Gln-Asp-Met-Gln-Leu-Gly-Arg substrate is cleaved into 2 fragments Streptococcus pyogenes ?
-
 ?
Cys-Val-Val-Ala-Ser-Gln-Leu-Arg-Ala-Asn-Ile-Ser-His-Lys-Asp-Met-Gln-Leu-Gly-Arg
-
 Streptococcus pyogenes ?
-
 ?
additional information no substrate: Cys-Val-Val-Ala-Ser-Gln-Leu-Arg-Ala-Asn-Ile-His-Pro-Lys-Asp-Met-Gln-Leu-Gly-Arg Streptococcus pyogenes ?
-
 ?

Synonyms

Synonyms Comment Organism
SCPA
-
 Streptococcus pyogenes