Literature summary for 3.4.21.109 extracted from

Maiwald, A.; Hammami, M.; Wagner, S.; Heine, A.; Klebe, G.; Steinmetzer, T.
Changing the selectivity profile - from substrate analog inhibitors of thrombin and factor Xa to potent matriptase inhibitors (2016), J. Enzyme Inhib. Med. Chem., 31, 89-97 .

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Crystallization (Commentary)

Crystallization (Comment)	Organism
in complex with inhibitor D-hTyr-Ala-4-amidinobenzylamide	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
D-hTyr-Ala-4-amidinobenzylamide	compound has a 10fold reduced activity against thrombin and factor Xa	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9Y5Y6	-	-

Synonyms

Synonyms	Comment	Organism
ST14	-	Homo sapiens
suppressor of tumorigenicity 14 protein	-	Homo sapiens

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.000026	-	D-hTyr-Ala-4-amidinobenzylamide	pH 8.0, temperature not specified in the publication	Homo sapiens

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Release 2023.1 (January 2023)