Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Epidermal growth factor | stimulates the release of matripase/hepatocyte growth factor activator inhibitor-1 complexes | Homo sapiens | |
Trypsin | activates membrane-bound, latent matripase on the cell surface | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell surface | - |
Homo sapiens | 9986 | - |
membrane | - |
Homo sapiens | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
75000 | - |
by immunoblotting or zymography | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast carcinoma cell | - |
Homo sapiens | - |
BT-20 cell | low level | Homo sapiens | - |
Colo-201 cell | high level | Homo sapiens | - |
colonic cancer cell line | - |
Homo sapiens | - |
DLD-1 cell | high level | Homo sapiens | - |
KATO-III cell | low level | Homo sapiens | - |
MCF-7 cell | low level | Homo sapiens | - |
MKN-1 cell | low level | Homo sapiens | - |
MKN-28 cell | low level | Homo sapiens | - |
MKN-45 cell | high level | Homo sapiens | - |
MKN-74 cell | high level | Homo sapiens | - |
additional information | stomach carcinoma cell line, low level in AZ521 cell, SCH cell, STKM-2 cell, MDA-MB cell, MMK-29 cell, YLC cell, KKI-cell, LU-65 cell and A549 cell,high level in STKM-1, RCM-1 cell, LU-99 cell and VMRC-LCP cell | Homo sapiens | - |
NUGC-3 cell | low level | Homo sapiens | - |
SW-480 cell | high level | Homo sapiens | - |
WiDr cell | high level | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Boc-Glu-Ala-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | ? | - |
? | |
Gelatin + H2O | - |
Homo sapiens | ? | - |
? |