Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
D482Y | inhibited activation of matriptase | Homo sapiens |
D519Y | inhibited activation of matriptase | Homo sapiens |
D555Y | inhibited activation of matriptase | Homo sapiens |
D598Y | inhibited activation of matriptase | Homo sapiens |
G149N | results in production of only nonprocesse, full-lenth matriptase | Homo sapiens |
N109Q | no reduced formation of matriptase-HAI-1-complex | Homo sapiens |
N302Q | reduced formation of matriptase-HAI-1-complex | Homo sapiens |
N485Q | no reduced formation of matriptase-HAI-1-complex | Homo sapiens |
N772Q | reduced formation of matriptase-HAI-1-complex | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | one-chain zymogen is converted to an active two-chain protease, enzyme with mutation in its catalytic triad is unable to undergo this activational cleavage | Homo sapiens |