Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ucf-101 | 0.02 mM abrogates the death effect of the TNF-alpha + zVAD combination | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | HtrA2 relocates to the cytoplasm upon apoptosis | Homo sapiens | 5737 | - |
mitochondrion | normally expression of HtrA2, enzyme does not leave the mitochondria upon the TNF-alpha + zVAD-induced cell death in neutrophils | Homo sapiens | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neutrophil | from the peripheral blood of healthy donors | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
X-linked inhibitor of apoptosis protein + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Omi/HtrA2 | - |
Homo sapiens |
serine protease | - |
Homo sapiens |