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Literature summary for 3.4.21.108 extracted from

  • Murwantoko, C.; Yano, M.; Ueta, Y.; Murasaki, A.; Kanda, H.; Oka, C.; Kawaichi, M.
    Binding of proteins to the PDZ domain regulates proteolytic activity of HtrA1 serine protease (2004), Biochem. J., 381, 895-904.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.108

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli BL21 (DE3) Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
with Ni-NTA-agarose column Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 peptide derived from type III collagen alpha1 C-propeptide does not activate nor significantly bind to HtrA2 as compared to HtrA1 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
reduced bovine serum albumin HtrA2-Opt peptides stimulate the delta N-HtrA1 protease activity more than 3fold Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
high temperature requirement A serine protease
-
 Homo sapiens
HtrA2/Omi
-
 Homo sapiens