Any feedback?
Literature summary for 3.4.21.107 extracted from
- Independent regulation of MucD, an HtrA-like protease in Pseudomonas aeruginosa, and the role of its proteolytic motif in alginate gene regulation (2006), J. Bacteriol., 188, 3134-3137.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene mucD is encoded in the algT-mucABCD operon, mapping of the transcriptional start site for a mucD promoter, PmucD within mucC, expression of S217A mutant single-copy gene mucD217 in strain PAO-derived mutant strains with defects in known regulators for alginate production | Pseudomonas aeruginosa |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| S217A | MucD altered in the protease motif is defective in temperature resistance and alginate gene regulation | Pseudomonas aeruginosa |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Pseudomonas aeruginosa | MucD negatively regulates alginate production on genetic level, MucD-deficient strain show temperature-dependent alginate production, while MucD-containing strains do not, which is independent of MucD proteolytic activity, overview | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas aeruginosa | - |
mucoid strain FRD1 and nonmucoid strain PAO1, gene mucD encoded in the algT-mucABCD operon | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | MucD negatively regulates alginate production on genetic level, MucD-deficient strain show temperature-dependent alginate production, while MucD-containing strains do not, which is independent of MucD proteolytic activity, overview | Pseudomonas aeruginosa | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HtrA-like protease | - |
Pseudomonas aeruginosa |
| More | the enzyme is a member of the the HtrA/DegP family of endoserine proteases | Pseudomonas aeruginosa |
| MucD | - |
Pseudomonas aeruginosa |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
