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Literature summary for 3.4.21.107 extracted from

  • Skorko-Glonek, J.; Wawrzynow, A.; Krzewski, K.; Kurpierz, K.; Lipinska, B.
    Site-directed mutagenesis of the HtrA (DegP) serine protease, whose proteolytic activity is indispensable for Escherichia coli survival at elevated temperatures (1995), Gene, 163, 47-52.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Escherichia coli

Protein Variants

Protein Variants Comment Organism
H105R loss of protease activity, no change in secondary structure Escherichia coli
S210A loss of protease activity, no change in secondary structure Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
51000
-
precursor protein, SDS-PAGE Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Escherichia coli involved in the degradation of damaged proteins, enzyme is indispensable for bacterial survival at elevated temperatures ?
-
?
Protein + H2O Escherichia coli
-
?
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
wild-type, S210A and H105R mutant Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-casein + H2O
-
Escherichia coli ?
-
?
additional information involved in the degradation of damaged proteins, enzyme is indispensable for bacterial survival at elevated temperatures Escherichia coli ?
-
?
Protein + H2O
-
Escherichia coli ?
-
?