Cloned (Comment) | Organism |
---|---|
fusion protein with maltose-binding protein | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-amidinophenylmethylsulfonyl fluoride | complete inhibition at 1 mM | Homo sapiens | |
antithrombin III | 76% inhibition at 0.003 mM, 1U/ml heparin enhances inhibition | Homo sapiens | |
Aprotinin | 90% inhibition at 0.008 mM | Homo sapiens | |
additional information | no inhibition by soybean trypsin inhibitor and tissue factor pathway inhibitor | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Homo sapiens | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | optimal concentration: 5 mM | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Protein + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
factor X + H2O | activates factor X in the presence of factor VII | Homo sapiens | ? | - |
? | |
additional information | enzyme does not cleave factor VII R152E mutant | Homo sapiens | ? | - |
? | |
Protein + H2O | - |
Homo sapiens | ? | - |
? | |
zymogen factor VII + H2O | cleaves between Arg152 and Ile153 | Homo sapiens | factor VIIa | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 8 | - |
Homo sapiens |