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Literature summary for 3.4.21.105 extracted from

  • Yu, L.; Lee, T.; Lin, N.; Wolf, M.J.
    Affecting Rhomboid-3 function causes a dilated heart in adult Drosophila (2010), PLoS Genet., 6, e1000969.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
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-
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Source Tissue

Source Tissue Comment Organism Textmining
embryo
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Drosophila melanogaster
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heart
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Drosophila melanogaster
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pupa
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Drosophila melanogaster
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Synonyms

Synonyms Comment Organism
rhomboid-3
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Drosophila melanogaster

General Information

General Information Comment Organism
malfunction using optical coherence tomography to examine the cardiac function in adult Drosophila from a set of molecularly defined genomic deficiencies an abnormally enlarged cardiac chamber in a series of deficiency mutants spanning the rhomboid 3 locus are identified. It is demonstrated that rhomboid 3 mediated activation of the EGF receptor pathway is necessary for proper adult cardiac function Drosophila melanogaster