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Literature summary for 3.4.21.105 extracted from

  • Urban, S.; Lee, J.R.; Freeman, M.
    Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases (2001), Cell, 107, 173-182.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane intramembrane enzyme Drosophila sp. (in: flies) 16020
-
membrane intramembrane enzyme Homo sapiens 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Spitz + H2O Drosophila sp. (in: flies) the rhomboid active site in directly cleaves the membrane-anchored TGFalpha-like growth factor Spitz within its transmembarne domain ?
-
?
Spitz + H2O Homo sapiens the rhomboid active site in directly cleaves the membrane-anchored TGFalpha-like growth factor Spitz within its transmembarne domain ?
-
?

Organism

Organism UniProt Comment Textmining
Drosophila sp. (in: flies)
-
-
-
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Spitz + H2O
-
Drosophila sp. (in: flies) ?
-
?
Spitz + H2O
-
Homo sapiens ?
-
?
Spitz + H2O the rhomboid active site in directly cleaves the membrane-anchored TGFalpha-like growth factor Spitz within its transmembarne domain Drosophila sp. (in: flies) ?
-
?
Spitz + H2O the rhomboid active site in directly cleaves the membrane-anchored TGFalpha-like growth factor Spitz within its transmembarne domain Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
RHBDL2
-
Homo sapiens
rhomboid-1
-
Drosophila sp. (in: flies)