Literature summary for 3.4.21.104 extracted from

Ojurongbe, O.; Antony, J.S.; Van Tong, H.; Meyer, C.G.; Akindele, A.A.; Sina-Agbaje, O.R.; Kremsner, P.G.; Velavan, T.P.
Low MBL-associated serine protease 2 (MASP-2) levels correlate with urogenital schistosomiasis in Nigerian children (2015), Trop. Med. Int. Health, 20, 1311-1319 .

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Application

Application	Comment	Organism
medicine	MASP-2 serum levels vary between younger children (12 years and less) and older children (above 12 years) and adults. Younger children with a patent infection with with Schistosoma haematobium have significantly lower MASP-2 serum levels than uninfected children. Older children and adults with a current infection have higher serum MASP-2 levels than controls. mannose-binding lectin serum levels correlate positively with MASP-2 serum levels. MASP2 secretor haplotypes are associated with MASP-2 serum levels in healthy subjects. The heterozygous MASP2 P126L variant is associated with reduced serum MASP-2 levels	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	O00187	-	-

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Release 2023.1 (January 2023)