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BRENDA support

Literature summary for 3.4.21.104 extracted from

  • Phillips, A.E.; Toth, J.; Dodds, A.W.; Girija, U.V.; Furze, C.M.; Pala, E.; Sim, R.B.; Reid, K.B.; Schwaeble, W.J.; Schmid, R.; Keeble, A.H.; Wallis, R.
    Analogous interactions in initiating complexes of the classical and lectin pathways of complement (2009), J. Immunol., 182, 7708-7717.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
ficolin
-
Rattus norvegicus
mannan-binding lectin
-
Rattus norvegicus
additional information in the lectin pathway MASP-2 autoactivates Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
90000
-
SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
complement component C2 + H2O Rattus norvegicus
-
?
-
?
complement component C4 + H2O Rattus norvegicus
-
?
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q9JJS8
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C2 + H2O
-
Rattus norvegicus ?
-
?
complement component C4 + H2O
-
Rattus norvegicus ?
-
?

Subunits

Subunits Comment Organism
homodimer
-
Rattus norvegicus

Synonyms

Synonyms Comment Organism
MASP-2
-
Rattus norvegicus
MBL-associated serine protease-2
-
Rattus norvegicus