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Literature summary for 3.4.21.104 extracted from

  • Ytting, H.; Christensen, I.J.; Thiel, S.; Jensenius, J.C.; Svendsen, M.N.; Nielsen, L.; Lottenburger, T.; Nielsen, H.J.
    Biological variation in circulating levels of mannan-binding lectin (MBL) and MBL-associated serine protease-2 and the influence of age, gender and physical exercise (2007), Scand. J. Immunol., 66, 458-464.
    View publication on PubMed
Search for more literature for 3.4.21.104

Application

Application Comment Organism
diagnostics MASP-2 may have potential as clinical biomarkers in colorectal cancer Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens MASP-2 is a central component of the MBL pathway of complement activation, MBL and MASP-2 levels in serum and plasma of healthy individuals are similar and independent of gender and age, while they are increased in colorectal cancer patients, overview ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
colorectal cancer cell
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 Homo sapiens
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plasma
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 Homo sapiens
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serum
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 Homo sapiens
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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 MBL and MASP-2 levels in serum and plasma of healthy individuals over a long time period, independent of gender and age, quantitative anaylsis, overview Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information MASP-2 is a central component of the MBL pathway of complement activation, MBL and MASP-2 levels in serum and plasma of healthy individuals are similar and independent of gender and age, while they are increased in colorectal cancer patients, overview Homo sapiens ?
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 ?

Synonyms

Synonyms Comment Organism
MBL-associated serine protease-2
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 Homo sapiens