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Literature summary for 3.4.21.104 extracted from
- Lectin pathway of bony fish complement: identification of two homologs of the mannose-binding lectin associated with MASP2 in the common carp (Cyprinus carpio) (2006), J. Immunol., 177, 5471-5479.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| MASP2, DNA and amino acid sequence determination and anaylsis, phylogenetic analysis, MASP2 arose before the emergence of bony fish | Cyprinus carpio |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Cyprinus carpio |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| complement component C4 + H2O | Cyprinus carpio | - |
complement component C4b + ? | - |
? | |
| additional information | Cyprinus carpio | MASP-2 is associated with two mannose-binding lectin homologues, one, designated GalBL, corresponds to the MBL-like molecule with the galactose specificity, the other is an authentic MBL with mannose specificity, overview, bony fish have developed a diverged set of MBL homologs, which function in the lectin complement pathway | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cyprinus carpio | Q3V5Q0 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| complement component C4 + H2O | - |
Cyprinus carpio | complement component C4b + ? | - |
? | |
| complement component C4 + H2O | no formation of C4i | Cyprinus carpio | complement component C4b + ? | - |
? | |
| additional information | MASP-2 is associated with two mannose-binding lectin homologues, one, designated GalBL, corresponds to the MBL-like molecule with the galactose specificity, the other is an authentic MBL with mannose specificity, overview, bony fish have developed a diverged set of MBL homologs, which function in the lectin complement pathway | Cyprinus carpio | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MASP2 | - |
Cyprinus carpio |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
assay at | Cyprinus carpio |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Cyprinus carpio |
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Release 2023.1 (January 2023)
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