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Literature summary for 3.4.21.102 extracted from
- The lone S41 family C-terminal processing protease in Staphylococcus aureus is localized to the cell wall and contributes to virulence (2014), Microbiology, 160, 1737-1748.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cell wall | - |
Staphylococcus aureus | 5618 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Staphylococcus aureus | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| C-terminal processing protease | - |
Staphylococcus aureus |
| CtpA | - |
Staphylococcus aureus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Staphylococcus aureus | expression of the ctpA gene encoding C-terminal processing protease is maximal upon exposure to conditions encountered during infection | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | disruption of the ctpA gene leads to decreased heat tolerance and increased sensitivity when exposed to components of the host immune system. The ctpA mutant strain is attenuated for virulence in a murine model of infection | Staphylococcus aureus |
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