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Literature summary for 3.4.21.102 extracted from

  • Reiling, S.A.; Jansen, J.A.; Henley, B.J.; Singh, S.; Chattin, C.; Chandler, M.; Rowen, D.W.
    Prc protease promotes mucoidy in mucA mutants of Pseudomonas aeruginosa (2005), Microbiology, 151, 2251-2261.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene prc from three strains, DNA and amino acid sequence determination and analysis, prc is located in a gene cluster encoding an extreme stress response system composed of anti-sigma factor MucA, negative regulator MucB, and ECF alternative sigma factor AlgU, regulation, overview Pseudomonas aeruginosa

Localization

Localization Comment Organism GeneOntology No. Textmining
periplasm
-
Pseudomonas aeruginosa
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
anti-sigma factor MucA + H2O Pseudomonas aeruginosa the Prc protease degrades mutants forms of MucA, the enzyme activity does not affect alginate production in strains with wild-type MucA, but MucA22 mutants show the mucoid phenotype, overview ?
-
?

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
several strains, gene PA3257 or prc
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
anti-sigma factor MucA + H2O
-
Pseudomonas aeruginosa ?
-
?
anti-sigma factor MucA + H2O the Prc protease degrades mutants forms of MucA, the enzyme activity does not affect alginate production in strains with wild-type MucA, but MucA22 mutants show the mucoid phenotype, overview Pseudomonas aeruginosa ?
-
?

Synonyms

Synonyms Comment Organism
Prc protease
-
Pseudomonas aeruginosa