Inhibitors | Comment | Organism | Structure |
---|---|---|---|
micropeptin 478-A | potent inhibitor | synthetic construct | |
micropeptin 478-B | moderate inhibitor | synthetic construct | |
micropeptin HU1021 | weak inhibitor | synthetic construct | |
micropeptin HU1041 | weak inhibitor | synthetic construct | |
micropeptin HU1069 | weak inhibitor | synthetic construct | |
micropeptin HU895A | moderate inhibitor | synthetic construct | |
micropeptin HU895B | potent inhibitor | synthetic construct | |
micropeptin HU909 | potent inhibitor | synthetic construct | |
micropeptin HU975 | moderate inhibitor | synthetic construct | |
micropeptin HU989 | moderate inhibitor | synthetic construct | |
additional information | lowest inhibition concentrations of chymotrypsin for glyceric acid at position 7, while 3-sulfoglyceric acid derivatives are less potent and disulfoglyceric acid derivatives exert much higher IC50's | synthetic construct |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | required for catalysis | synthetic construct |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
synthetic construct | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-Gly-Gly-p-nitroanilide + H2O | - |
synthetic construct | succinyl-Gly-Gly + p-nitroaniline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
chymotrypsin | - |
synthetic construct |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0028 | - |
micropeptin HU909 | at 37°C, in 50 mM Tris-HCl buffer, 100 mM NaCl, 1 mM CaCl2 and 1 mM HCl | synthetic construct | |
0.0052 | - |
micropeptin 478-A | at 37°C, in 50 mM Tris-HCl buffer, 100 mM NaCl, 1 mM CaCl2 and 1 mM HCl | synthetic construct | |
0.0054 | - |
micropeptin HU895B | at 37°C, in 50 mM Tris-HCl buffer, 100 mM NaCl, 1 mM CaCl2 and 1 mM HCl | synthetic construct | |
0.0182 | - |
micropeptin HU989 | at 37°C, in 50 mM Tris-HCl buffer, 100 mM NaCl, 1 mM CaCl2 and 1 mM HCl | synthetic construct | |
0.0196 | - |
micropeptin HU895A | at 37°C, in 50 mM Tris-HCl buffer, 100 mM NaCl, 1 mM CaCl2 and 1 mM HCl | synthetic construct | |
0.024 | - |
micropeptin HU975 | at 37°C, in 50 mM Tris-HCl buffer, 100 mM NaCl, 1 mM CaCl2 and 1 mM HCl | synthetic construct | |
0.072 | - |
micropeptin 478-B | at 37°C, in 50 mM Tris-HCl buffer, 100 mM NaCl, 1 mM CaCl2 and 1 mM HCl | synthetic construct | |
0.1 | - |
micropeptin HU1069 | at 37°C, in 50 mM Tris-HCl buffer, 100 mM NaCl, 1 mM CaCl2 and 1 mM HCl | synthetic construct | |
0.1 | - |
micropeptin HU1021 | at 37°C, in 50 mM Tris-HCl buffer, 100 mM NaCl, 1 mM CaCl2 and 1 mM HCl | synthetic construct | |
0.1 | - |
micropeptin HU1041 | at 37°C, in 50 mM Tris-HCl buffer, 100 mM NaCl, 1 mM CaCl2 and 1 mM HCl | synthetic construct |