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Literature summary for 3.4.19.5 extracted from

  • Jozic, D.; Kaiser, J.T.; Huber, R.; Bode, W.; Maskos, K.
    X-ray Structure of isoaspartyl dipeptidase from E. coli: a dinuclear zinc peptidase evolved from amidohydrolases (2003), J. Mol. Biol., 332, 243-256.
    View publication on PubMed
Search for more literature for 3.4.19.5

Cloned(Commentary)

Cloned (Comment) Organism
-
 Escherichia coli

Crystallization (Commentary)

Crystallization (Comment) Organism
sitting drop vapor diffusion method, crystal structure in the absence and presence of the phosphinic inhibitor Asp-PSI[PO2CH2]-LeuOH Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
Asp-PSI[PO2CH2]-LeuOH
-
 Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Zinc two catalytic zinc ions are surrounded by four His Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P39377
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
iso-Asp-Gly + H2O
-
 Escherichia coli ?
-
 ?
iso-Asp-Leu + H2O best substrate Escherichia coli ?
-
 ?

Subunits

Subunits Comment Organism
More the quarternary structure of the enzyme is octameric and can be described as a tetramer od dimers. Each subunit folds into two distinct domains Escherichia coli