Literature summary for 3.4.19.3 extracted from

Valdivia, A.; Irazusta, J.; Fernandez, D.; Mugica, J.; Ochoa, C.; Casis, L.
Pyroglutamyl peptidase I and prolyl endopeptidase in human semen: increased activity in necrozoospermia (2004), Regul. Pept., 122, 79-84.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	enzyme may participate in regulating the levels of seminal thyrotropin-relasing hormone analogues and in mediating sperm death associated with necrozoospermia	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
semen	highest level in particulate sperm fraction. Increased activity in necrozoospermia	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	enzyme may participate in regulating the levels of seminal thyrotropin-relasing hormone analogues and in mediating sperm death associated with necrozoospermia	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)