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Literature summary for 3.4.19.12 extracted from

  • Kang, X.; Sun, L.; Guo, K.; Shu, H.; Yao, J.; Qin, X.; Liu, Y.
    Serum protein biomarkers screening in HCC patients with liver cirrhosis by ICAT-LC-MS/MS (2010), J. Cancer Res. Clin. Oncol., 136, 1151-1159.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
liver healthy persons, and liver cirrhosis and HCC patients, quantitative USP44 determination, overview Homo sapiens
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Synonyms

Synonyms Comment Organism
ubiquitin carboxyl-terminal hydrolase 44
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Homo sapiens
ubiquitin-specific protease 44
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Homo sapiens
USP44
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Homo sapiens

General Information

General Information Comment Organism
malfunction the deubiquitinating enzyme USP44 is a critical regulator of the spindle checkpoint, dysregulation of the spindle checkpoint can contribute to birth defects and tumorigenesis Homo sapiens
metabolism USP44 is a member of the ubiquitin proteasome pathway controlling intracellular protein degradation, functioning to maintain ubiquitin balance by associating with ubiquitin and by releasing ubiquitin from tandemly conjugated ubiquitin monomers and small adducts or unfolded proteins Homo sapiens
physiological function USP44 is a member of the ubiquitin proteasome pathway controlling intracellular protein degradation, functioning to maintain ubiquitin balance by associating with ubiquitin and by releasing ubiquitin from tandemly conjugated ubiquitin monomers and small adducts or unfolded proteins. Deubiquitinating enzyme USP44 is a critical regulator of the spindle checkpoint Homo sapiens