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Literature summary for 3.4.19.12 extracted from

  • Misaghi, S.; Galardy, P.J.; Meester, W.J.; Ovaa, H.; Ploegh, H.L.; Gaudet, R.
    Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate (2005), J. Biol. Chem., 280, 1512-1520.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop vapour diffusion method, 1.45 A resolution crystal structure of human UCH-L3 in complex with the inhibitor ubiquitin vinylmethyl ester Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
ubiquitin vinylmethyl ester inhibitor forms a covalent adduct with the active site cysteine of the enzyme Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P15374 expressed in Escherichia coli
-

Purification (Commentary)

Purification (Comment) Organism
recombinant Homo sapiens

Synonyms

Synonyms Comment Organism
ubiquitin hydrolase UCH-L3
-
Homo sapiens