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Literature summary for 3.4.19.12 extracted from

  • Kwon, J.; Wang, Y.L.; Setsuie, R.; Sekiguchi, S.; Sakurai, M.; Sato, Y.; Lee, W.W.; Ishii, Y.; Kyuwa, S.; Noda, M.; Wada, K.; Yoshikawa, Y.
    Developmental regulation of ubiquitin C-terminal hydrolase isozyme expression during spermatogenesis in mice (2004), Biol. Reprod., 71, 515-521.
    View publication on PubMed
Search for more literature for 3.4.19.12

Protein Variants

Protein Variants Comment Organism
additional information UCH-L1-deficient gad mice show progressively decreasing spermatogonial stem cell proliferation Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus the enzyme is involved in spermatogenesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
 wild-type and gad, i.e. gracile axonal dystrophy, mice, isozymes UCH-L1, UCH-L3, UCH-L4, and UCH-L5
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Mus musculus P15347
-
-
Mus musculus Q9R0P9
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information expression pattern of UCH isozymes in Sertoli cells, spermatids, spermatocytes, and spermatogonia, overview Mus musculus
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Sertoli cell UCH-L1 protein Mus musculus
-
Sertoli cell UCH-L1 may act during mitotic proliferation of spermatogonial stem cells Mus musculus
-
spermatid UCH-L3 protein Mus musculus
-
spermatid UCH-L3 may function in the meiotic differentiation of spermatocytes into spermatids Mus musculus
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spermatocyte UCH-L3 protein Mus musculus
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spermatocyte UCH-L3 may function in the meiotic differentiation of spermatocytes into spermatids Mus musculus
-
spermatogonium UCH-L1 protein Mus musculus
-
spermatogonium UCH-L1 may act during mitotic proliferation of spermatogonial stem cells Mus musculus
-
testis
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is involved in spermatogenesis Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
ubiquitin C-terminal hydrolase
-
 Mus musculus
UCH
-
 Mus musculus
UCH-L1
-
 Mus musculus
UCH-L3
-
 Mus musculus