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Literature summary for 3.4.18.1 extracted from

  • Lechner, A.M.; Assfalg-Machleidt, I.; Zahler, S.; Stoeckelhuber, M.; Machleidt, W.; Jochum, M.; Naegler, D.K.
    RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties (2006), J. Biol. Chem., 281, 39588-39597.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and anaylsis, expression of wild-type and mutant procathepsin X Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
plasma membrane
-
Homo sapiens 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens procathepsin X supports integrin alphavbeta3-dependent attachment and spreading of umbilical vein endothelial cells, overvie ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9UBR2
-
-

Source Tissue

Source Tissue Comment Organism Textmining
umbilical vein endothelial cell the enzyme accumulates in vesicles at lamellipodia Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information procathepsin X supports integrin alphavbeta3-dependent attachment and spreading of umbilical vein endothelial cells, overvie Homo sapiens ?
-
?
additional information direct interaction between the enzyme and integrin alphavbeta3, overview Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
cathepsin X
-
Homo sapiens