Literature summary for 3.4.18.1 extracted from

Cooke, G.S.; Campbell, S.J.; Bennett, S.; Lienhardt, C.; McAdam, K.P.; Sow, O.; Gustafson, P.; Mwangulu, F.; van Helden, P.; Fine, P.; Hoal, E.G.; Hill, A.V.
Mapping of a novel susceptibility locus suggests a role for MC3R and CTSZ in human tuberculosis (2008), Am. J. Respir. Crit. Care Med., 178, 203-207.

Search for more literature for 3.4.18.1

Cloned(Commentary)

Cloned (Comment)	Organism
genotype distributions of CTSZ and CTSZ3P in South African coloured population in metropolitan Cape Town, South Africa, genotyping, overview	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	the enzyme plays a role in immunity to pathogens including Mycobacterium tuberculosis, variation in the melanocortin 3 receptor and cathepsin Z genes play a role in the pathogenesis of tuberculosis in West African populations	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9UBR2	gene CTSZ, South African coloured population in metropolitan Cape Town, South Africa	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	the enzyme plays a role in immunity to pathogens including Mycobacterium tuberculosis, variation in the melanocortin 3 receptor and cathepsin Z genes play a role in the pathogenesis of tuberculosis in West African populations	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
CTSZ	-	Homo sapiens

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Release 2023.1 (January 2023)