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Literature summary for 3.4.18.1 extracted from

  • Krueger, S.; Kalinski, T.; Hundertmark, T.; Wex, T.; Kuster, D.; Peitz, U.; Ebert, M.; Nagler, D.K.; Kellner, U.; Malfertheiner, P.; Naumann, M.; Rocken, C.; Roessner, A.
    Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer (2005), J. Pathol., 207, 32-42.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens cathepsin X plays a role not only in the chronic inflammation of gastric mucosa but also in the tumourigenesis of gastric cancer ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
gastric cancer cell
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Homo sapiens
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gastric mucosa upregulation in gastric cancer compared to non-neoplastic mucosa. Patients with Helicobacter pylori gastritis show significantly higher cathepsin X mRNA (2.5fold) and protein (1.6fold) expression than Helicobacter pylori-negative partients Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information cathepsin X plays a role not only in the chronic inflammation of gastric mucosa but also in the tumourigenesis of gastric cancer Homo sapiens ?
-
?