Any feedback?
Literature summary for 3.4.17.8 extracted from
- Reactivity of penicillin-binding proteins with peptidoglycan-mimetic beta-lactams: whats wrong with these enzymes? (2006), Biochemistry, 45, 15873-15883.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| (5R,6R)-6-[(7-ammonio-7-carboxylatoheptanoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate | - |
Escherichia coli |  |
| 6-beta(D-alpha-aminopimelyl)-aminopenicillanic acid | - |
Escherichia coli | |
| 6-beta(N-acetyl-L-alanyl-gamma-D-glutamyl-L-alanyl)-aminopenicillanic acid | - |
Escherichia coli | |
| 7-beta(D-alpha-aminopimelyl)-aminocephalosporanic acid | - |
Escherichia coli | |
| benzylpenicillin | - |
Escherichia coli | |
| cephalothin | - |
Escherichia coli | |
| additional information | synthesis and inhibitory potency of beta-lactam derivatives, overview | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
gene pbp5 | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DD-peptidase | - |
Escherichia coli |
| PBP5 | - |
Escherichia coli |
| penicillin-binding protein 5 | - |
Escherichia coli |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Escherichia coli |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
assay at | Escherichia coli |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | - |
Escherichia coli |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
