Inhibitors | Comment | Organism | Structure |
---|---|---|---|
6-gingerol | inhibition of the ACE2 enzyme | Homo sapiens | |
amentoflvaone | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
andrographolide | inhibition of the ACE2 enzyme | Homo sapiens | |
apigenin | inhibition of the ACE2 enzyme | Homo sapiens | |
arbidol | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
artemisnin | inhibition of the ACE2 enzyme | Homo sapiens | |
asparoside C | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
AY-NH2 | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
Berberine | inhibition of the ACE2 enzyme | Homo sapiens | |
beta-sitosterol | inhibition of the ACE2 enzyme | Homo sapiens | |
bis-demethoxy curcumin | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
cepharanthine | potential inhibitor of the SARS-CoV-2-S protein:ACE2 complex | Homo sapiens | |
chebulagic acid | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
crisimaritin | inhibition of the ACE2 enzyme | Homo sapiens | |
cucurbitacin B | inhibition of the ACE2 enzyme | Homo sapiens | |
curcumin | inhibition of the ACE2 enzyme | Homo sapiens | |
cynaropicrin | inhibition of the ACE2 enzyme | Homo sapiens | |
darunavir | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
denopamine | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
dithymoquinone | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
ergoloid | potential inhibitor of the SARS-CoV-2-S protein:ACE2 complex | Homo sapiens | |
eriodictyol | potential inhibitor of the SARS-CoV-2-S protein:ACE2 complex | Homo sapiens | |
favipiravir | potential inhibitor of the SARS-CoV-2-S protein:ACE2 complex | Homo sapiens | |
hesperidin | inhibition of the ACE2 enzyme; inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
hispudulin | inhibition of the ACE2 enzyme | Homo sapiens | |
hydroxychloroquine | potential inhibitor of the SARS-CoV-2-S protein:ACE2 complex | Homo sapiens | |
hypericin | potential inhibitor of the SARS-CoV-2-S protein:ACE2 complex | Homo sapiens | |
isoniazid pyruvate | potential inhibitor of the SARS-CoV-2-S protein:ACE2 complex | Homo sapiens | |
isothymol | inhibition of the ACE2 enzyme | Homo sapiens | |
ivermectin | inhibition of the ACE2 enzyme; potential inhibitor of the SARS-CoV-2-S protein:ACE2 complex | Homo sapiens | |
menthol | potential inhibitor of the SARS-CoV-2-S protein:ACE2 complex | Homo sapiens | |
MLN-4760 | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
additional information | inhibitors of SARS-CoV-2:ACE2 binding | Homo sapiens | |
naringin | inhibition of the ACE2 enzyme | Homo sapiens | |
neoandrographolide | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
Nitrofurantoin | potential inhibitor of the SARS-CoV-2-S protein:ACE2 complex | Homo sapiens | |
orientin | inhibition of the ACE2 enzyme | Homo sapiens | |
paritaprevir | inhibition of the ACE2 enzyme | Homo sapiens | |
piceatannol | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
pseudojervine | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
quercetin | inhibition of the ACE2 enzyme | Homo sapiens | |
quercetin-3-O-galatosyl-rhamnosyl-glucoside | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
raspberry ketone | potential inhibitor of the SARS-CoV-2-S protein:ACE2 complex | Homo sapiens | |
rutin | inhibition of the ACE2 enzyme | Homo sapiens | |
rutin DAB10 | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
saikosaponin A | inhibition of the ACE2 enzyme | Homo sapiens | |
spinochrome A | inhibitor of SARS-CoV-2-(receptor binding domain):ACE2 complex | Homo sapiens | |
thymoquinone | potential inhibitor of the SARS-CoV-2-S protein:ACE2 complex | Homo sapiens | |
vitexin | inhibition of the ACE2 enzyme | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9BYF1 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
oral mucosa | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
ACE2 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | SARS-CoV-2 binds to the angiotensin converting enzyme 2 (ACE2) receptor of the host cells through the viral surface spike glycoprotein (S-protein). ACE2 is expressed in the oral mucosa and can therefore constitute an essential route for entry of SARS-CoV-2 into hosts through the tongue and lung epithelial cells | Homo sapiens |