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Literature summary for 3.4.17.23 extracted from

  • Feng, Y.; Hans, C.; McIlwain, E.; Varner, K.J.; Lazartigues, E.
    Angiotensin-converting enzyme 2 over-expression in the central nervous system reduces angiotensin-II-mediated cardiac hypertrophy (2012), PLoS ONE, 7, e48910.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
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Synonyms

Synonyms Comment Organism
ACE2
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Mus musculus
angiotensin converting enzyme 2
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Mus musculus

General Information

General Information Comment Organism
malfunction ACE2 over-expression in the brain decreases Ang-II mediated cardiac hypertrophy and collagen deposition, reduces urinary norepinephrine levels and partially protectes syn-hACE2 transgenic (SA) mice, in which the human ACE2 transgene is selectively targeted to neurons, from sympathetic-mediated cardiac hypertrophy and fibrosis Mus musculus