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Literature summary for 3.4.17.23 extracted from

  • Feng, Y.; Wan, H.; Liu, J.; Zhang, R.; Ma, Q.; Han, B.; Xiang, Y.; Che, J.; Cao, H.; Fei, X.; Qiu, W.
    The angiotensin-converting enzyme 2 in tumor growth and tumor-associated angiogenesis in non-small cell lung cancer (2010), Oncol. Rep., 23, 941-948.
    View publication on PubMed

Application

Application Comment Organism
pharmacology ACE2 might be a target for treatment of non-small cell lung cancer Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information overexpression of ACE 2 might have a protective effect by inhibiting cell growth and vascular endothelial growth factor a production in vitro Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Homo sapiens 5737
-
membrane
-
Homo sapiens 16020
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
Homo sapiens
-
non-small cell lung cancer cell decreased ACE2 expression, expression profile in relation to clinicopathological factors, e.g. smoking, overview Homo sapiens
-

Synonyms

Synonyms Comment Organism
ACE2
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens angiotensin II downregulates ACE2, but increases the expression of vascular endothelial growth factor and type receptor AT1-R, overview down

General Information

General Information Comment Organism
metabolism ACE2 ia a component of the renin-angiotensin system, RAS Homo sapiens