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Literature summary for 3.4.17.23 extracted from

  • Feng, Y.; Yue, X.; Xia, H.; Bindom, S.M.; Hickman, P.J.; Filipeanu, C.M.; Wu, G.; Lazartigues, E.
    Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulation (2008), Circ. Res., 102, 729-736.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine ACE2 offers a new target for the treatment of hypertension and other cardiovascular diseases Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus ACE2 plays a pivotal role in the central regulation of blood pressure and volume homeostasis ?
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?

Organism

Organism UniProt Comment Textmining
Mus musculus Q8R0I0
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-

Source Tissue

Source Tissue Comment Organism Textmining
brain overexpression to the forebrain, essentially the subfornical organ, inhibits both pressor and drinking responses resulting from intracerebroventricular administration of Ang-II Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information ACE2 plays a pivotal role in the central regulation of blood pressure and volume homeostasis Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
ACE2
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Mus musculus
angiotensin-converting enzyme 2
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Mus musculus
hACE2
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Mus musculus